Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 25mg | ||||
360 pill | 25mg | $136.99 | $0.38 | |
180 pill | 25mg | $89.99 | $0.50 | |
120 pill | 25mg | $65.99 | $0.55 | |
90 pill | 25mg | $55.99 | $0.62 | |
60 pill | 25mg | $38.99 | $0.65 | |
30 pill | 25mg | $22.99 | $0.75 | |
Dosage: 50mg | ||||
360 pill | 50mg | $237.99 | $0.66 | |
180 pill | 50mg | $129.99 | $0.72 | |
120 pill | 50mg | $94.99 | $0.79 | |
90 pill | 50mg | $80.99 | $0.90 | |
60 pill | 50mg | $55.99 | $0.94 | |
30 pill | 50mg | $32.99 | $1.10 | |
Dosage: 100mg | ||||
360 pill | 100mg | $323.99 | $0.90 | |
180 pill | 100mg | $175.99 | $0.98 | |
120 pill | 100mg | $126.99 | $1.06 | |
90 pill | 100mg | $105.99 | $1.18 | |
60 pill | 100mg | $73.99 | $1.24 | |
30 pill | 100mg | $43.99 | $1.47 |

Desyrel Description
Overview of Desyrel (Trazodone)
Desyrel, known generically as trazodone, is a medication commonly prescribed in the United States to manage depression and associated conditions such as anxiety and sleep disturbances. It belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs). This medication is valued for its dual action, which helps balance serotonin levels in the brain, contributing to mood improvement and better sleep. Unlike some antidepressants, trazodone is often preferred for its sedative properties, making it beneficial for patients experiencing insomnia alongside depression.
How Desyrel Works
Desyrel works by influencing the neurotransmitter serotonin, which plays a role in mood regulation. It acts by blocking certain serotonin receptors while simultaneously inhibiting serotonin reuptake. This dual mechanism enhances serotonin activity in the central nervous system. The result is an improvement in mood, alleviation of anxiety symptoms, and enhancement of sleep quality. Due to its sedative effect, trazodone is sometimes used off-label for sleep disorders, even in patients without depression.
Typical Use and Dosage
In the USA, Desyrel is usually prescribed at lower doses for sleep issues and higher doses for depression. Patients typically begin with a small dose, increasing gradually as advised by a healthcare professional. It is taken orally, usually once or twice daily, with or without food. Because of its sedative effects, it may be recommended to take it at bedtime. Adherence to the prescribed dose and schedule is crucial to minimize side effects and optimize results. It’s important to follow the guidance of your healthcare provider and not to adjust the dosage independently.
Potential Benefits of Desyrel
Many patients report noticeable improvements in their mood within a few weeks of starting Desyrel. Its sedative properties can ease sleep difficulties that often accompany depression. Another advantage is that trazodone tends to cause fewer weight gain issues and sexual side effects compared to alternative antidepressants. It’s also considered to have a relatively favorable safety profile when used responsibly and under medical supervision.
Possible Side Effects and Precautions
While Desyrel provides significant benefits, it can cause side effects. Common reactions include dizziness, dry mouth, drowsiness, and headache. Some users may experience blurred vision or feeling faint, particularly when standing up quickly. Rarely, trazodone can cause priapism—a rare but serious condition involving prolonged and painful erections. Patients should report any unusual or severe side effects to their healthcare provider promptly. Caution is advised when combining Desyrel with other CNS depressants or alcohol, as these can enhance sedative effects and impair alertness.
Considerations for Use
Desyrel is generally safe when prescribed and monitored appropriately. It is not suitable for everyone; individuals with a history of heart problems, suicidal thoughts, or certain medication interactions should discuss thoroughly with their doctor. Regular follow-up appointments help ensure the medication's effectiveness and safety. Patients should inform their healthcare provider about all medications they are taking to avoid adverse interactions.
Availability and Purchasing in the USA
In the United States, Desyrel is available through licensed pharmacies, including online pharmacies that comply with federal and state regulations. When purchasing medications online, it is essential to choose reputable sources to ensure medication quality and safety. Always consult your healthcare provider before starting or changing your medication regimen. Proper medical guidance optimizes treatment outcomes and minimizes risks associated with self-medication.